Start with an advanced intake designed to understand your skin, lifestyle, history, and longevity goals. Upload reports, lab results, previous visits, and any relevant documents into your personal hub, so your assigned expert can evaluate your profile with greater context.

Your skin, at its biological best.
Every day.
An adaptive ecosystem that brings together clinical rigor and lifestyle. YUKI brings prevention into your everyday life.
Early access is limited to the first 100 members.
Prevention starts too late
Biological data is collected every day, but it is rarely translated into skin decisions. Clinical longevity protocols exist, but remain inaccessible to most people. And anti-aging is still approached when signs are already visible.
Start ahead1B+ people track their biology daily.
But biological data is not connected to skin.
Up to €15K for clinical longevity protocols.
Clinical skin longevity remains out of reach.
Most interventions start after visible signs.
Prevention begins too late.
One daily plan. Multiple dimensions of care.
CONTEXTUAL SKINCAREYour barrier against climate and city life.
Adaptive nutritionSteady energy for your daily rhythm.
SYNERGISTIC SUPPLEMENTATIONSkin longevity, supported from within.
How the YUKI
Method works
A clinically guided journey from biological profile to adaptive daily protocol.
Request your access01. Biological Profile
02. Digital Bio Mapping
Your digital skin analysis helps identify key markers such as your Skin Stress Index, estimated skin biological age, and personalized skin-aging trajectory. This creates a clearer picture of how your skin may respond to time, environment, lifestyle, and daily stressors.
03. Medical Validation
Based on your intake, documents, and digital analysis, YUKI assigns you the most suitable Skin Longevity Expert for your case. Your expert reviews your profile and validates the direction of your journey.
04. Hyper-personalized Protocol
Receive your hyper-personalized adaptive protocol across skincare, nutrition, supplementation, and lifestyle. Your plan is designed around environmental factors, biomarker signals, and daily context — helping bring prevention into your real life.
WEATHER IN ROME
Mild humidity today. Add extra hydration to support barrier comfort in cooler air.
THE COMPANION
Your protocol, synced
Your routine is not a static checklist. It's a living system that responds to the world around you. YUKI synchronizes your biology with your environment, turning daily changes into longevity opportunities.

Cleanse gently after training
This supports comfort after sweat, heat, and urban exposure.
Remember to drink
Today's microclimate and planned workout may increase hydration needs.
You didn't sleep very well
Consider a 20-minute meditation or quiet rest before your workout.
One year of guided prevention
Un ecosistema adattivo che sincronizza nutrizione e skincare alla tua vita.
01
QUESTIONNAIRE
Advanced epigenetic quiz
02
AI SKIN ANALYSIS
AI-based photo/video analysis
1° OUTPUT
Risk index report
03
VIDEO CONSULTING
Your dedicated Skin Expert
04
2° OUTPUT
Your personalized protocol
Actives, medical recipes, nutraceuticals, face training, lifestyle
05
MONITORING LOOP
UV · PM2.5 · sleep · stress
06
H24 SUPPORT
Adapted every 45–60 days
07
6-MONTH REVIEW
Second video consult + re-scan
Developed with a multidisciplinary medical board

Nicola Marino
Researcher affiliated with the Women's Brain Foundation, Director of AEON Foundation. Collaborations with Harvard Medical School and Dana-Farber Cancer Institute.

Simone Cappilli
Medical doctor and specialist in Dermatology and Venereology, with expertise in aesthetic medicine and laser therapy. Author of numerous scientific publications in the field of non-invasive skin diagnostics.

Nino Favoriti
Specialist in Dermatology, Aesthetic Medicine and Laser Therapy.

Sacha Sorrentino
Longevity & Sport Nutritionist Villa Brasini. Integrates the nutritional and metabolic dimension into the protocol.
Everything your skin
longevity journey needs without fragmented costs
Without Yuki
Dermatologist / Skin longevity specialist
1–2 visits/year, avg. €150–300 per session
€25–50/mo
Nutritionist / Longevity coach
Ongoing monthly support
€250–750/mo
Wearables (Oura Ring + subscription)
Hardware + annual subscription
€20–30/mo
Premium wellness apps (Whoop, Levels...)
Single aspect, no skin integration
€20–40/mo
- Epigenetic questionnaire + AI analysis
- Skin Longevity Score + aging trajectory
- Dedicated Skin Longevity Expert
- Continuous adaptive protocol
- Real-time geo-environmental alerts
- Wearable sync (HRV, sleep, stress)
- Biological document hub
- Adaptive check every 45/60 days
Be the first to decode
your skin biology
Enter the YUKI waitlist to discover a new way to understand your skin biology and turn daily signals into a personalized path for prevention, consistency, and long-term skin vitality.